$ 49 / 50mg
999 in stock (can be backordered)
GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper) is a naturally occurring copper-bound tripeptide studied extensively for its role in collagen remodeling, wound healing, angiogenesis, and hair-follicle signaling. First identified in human plasma, GHK-Cu peptide has been the subject of over 100 published studies examining its broad regenerative and anti-inflammatory properties across multiple tissue types.
GHK-Cu peptide exerts its effects through multiple pathways: it delivers bioavailable copper to cells (essential for lysyl oxidase and collagen cross-linking), upregulates decorin and other extracellular matrix components, and modulates gene expression related to tissue remodeling. Research has shown it stimulates collagen I and III synthesis, promotes angiogenesis via VEGF upregulation, and supports hair-follicle growth in dermal papilla cell models.
Researchers studying skin and tissue regeneration often explore GHK-Cu alongside BPC-157 for gastric-peptide-based tissue repair, Snap-8 for expression-line reduction research, and Melanotan I for melanocyte-activation studies in dermatological models.
Each vial contains GHK-Cu peptide manufactured in the USA under ISO-certified conditions. Verified to ≥99% purity by HPLC analysis, with endotoxin screening below 0.1 EU/mg. Certificate of Analysis (COA) available upon request. For laboratory research use only.
Lyophilized GHK-Cu peptide should be stored at -20°C in a sealed container protected from light and moisture to maintain long-term stability. For reconstitution, use bacteriostatic water and gently swirl the vial until the powder is fully dissolved — never shake. Once reconstituted, store at 2–8°C (standard laboratory refrigeration) and use within 28 days. The copper-peptide complex is stable in aqueous solution under proper refrigeration, but researchers should avoid repeated freeze-thaw cycles by preparing single-use aliquots. Always use sterile technique when withdrawing from reconstituted vials. For research use only.
GHK-Cu was first identified in 1973 by Loren Pickart at the University of California, San Francisco, during studies on human plasma factors that promoted hepatocyte proliferation. Pickart observed that a low-molecular-weight fraction of human albumin contained a copper-binding tripeptide with potent tissue-remodeling activity. Since this initial discovery, GHK-Cu has been the subject of over 100 peer-reviewed publications indexed in PubMed. Broad gene-expression studies at the Broad Institute demonstrated that GHK-Cu modulates over 4,000 human genes, many involved in tissue repair, anti-oxidant defense, and stem-cell biology. Research groups at Seoul National University, the University of British Columbia, and various dermatology-focused institutions have published extensively on its extracellular matrix effects. GHK-Cu remains one of the most studied naturally occurring peptides in regenerative biology research. All referenced work pertains to preclinical and laboratory settings.
AgeFix GHK-Cu is verified to ≥99% purity by HPLC analysis and undergoes endotoxin screening to confirm levels below 0.1 EU/mg. Each batch is manufactured in the USA under ISO-certified conditions, with a Certificate of Analysis (COA) available upon request.
GHK-Cu is one of few peptides that delivers bioavailable copper directly to cells, activating copper-dependent enzymes like lysyl oxidase that are essential for collagen cross-linking. Its ability to modulate over 4,000 genes involved in tissue remodeling gives it a uniquely broad regenerative profile compared to single-pathway peptides in research models.
GHK-Cu should be reconstituted with bacteriostatic water by gently swirling until fully dissolved. Store reconstituted GHK-Cu at 2–8°C and use within 28 days. This product is for laboratory research use only and is not intended for human use.
